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Akira Murakami Selected Research

aurapten

7/2012Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice.
1/2010Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells.
1/2008Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin.
12/2006Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.
10/2006Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.
8/2005Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.
1/2004Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis.
10/2002Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells.
5/2002Rapid and convenient method for preparing aurapten-enriched product from hassaku peel oil: implications for cancer-preventive food additives.

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Akira Murakami Research Topics

Disease

52Neoplasms (Cancer)
06/2020 - 01/2000
29Carcinogenesis
12/2015 - 01/2000
27Inflammation (Inflammations)
01/2021 - 05/2002
15Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
10/2021 - 06/2004
14Colitis
07/2021 - 10/2003
13Dry Eye Syndromes (Dry Eye Syndrome)
07/2022 - 10/2007
10Cataract (Cataracts)
08/2022 - 11/2010
10Hereditary Corneal Dystrophies
09/2010 - 11/2002
9Colonic Neoplasms (Colon Cancer)
08/2014 - 01/2004
7Body Weight (Weight, Body)
05/2012 - 01/2002
7Open-Angle Glaucoma (Glaucoma, Open Angle)
02/2011 - 01/2006
6Wounds and Injuries (Trauma)
10/2017 - 12/2005
6Glaucoma
12/2015 - 12/2004
6Carcinoma (Carcinomatosis)
09/2010 - 07/2002
5Colorectal Neoplasms (Colorectal Cancer)
08/2014 - 10/2002
5Breast Neoplasms (Breast Cancer)
01/2013 - 01/2007
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
07/2021 - 07/2007
4Hepatocellular Carcinoma (Hepatoma)
02/2021 - 08/2005
4Retinitis Pigmentosa (Pigmentary Retinopathy)
11/2019 - 03/2011
4Macular Edema
01/2018 - 01/2014
4Pain (Aches)
10/2017 - 03/2009
4Multiple Myeloma
01/2013 - 05/2005
4Leukemia
01/2007 - 02/2003
3Seasonal Allergic Rhinitis (Hay Fever)
07/2022 - 01/2020
3Hypersensitivity (Allergy)
07/2022 - 01/2010
3Ulcerative Colitis
03/2022 - 10/2003
3Schizophrenia (Dementia Praecox)
03/2021 - 01/2020
3Mental Disorders (Mental Disorder)
03/2021 - 01/2020
3Obesity
09/2019 - 01/2010
3Low Tension Glaucoma
01/2019 - 12/2007
3Adenocarcinoma
01/2009 - 01/2004
3Atherosclerosis
04/2007 - 05/2006
3Neoplasm Metastasis (Metastasis)
09/2005 - 02/2005

Drug/Important Bio-Agent (IBA)

18Proteins (Proteins, Gene)FDA Link
01/2017 - 02/2002
16zerumboneIBA
11/2021 - 05/2002
11Messenger RNA (mRNA)IBA
11/2021 - 02/2005
11Dextran SulfateIBA
07/2021 - 02/2005
11CytokinesIBA
12/2015 - 01/2004
11PhytochemicalsIBA
01/2015 - 01/2000
11EnzymesIBA
01/2015 - 07/2004
11SesquiterpenesIBA
01/2015 - 05/2002
10AntioxidantsIBA
09/2014 - 03/2003
9Ophthalmic Solutions (Eye Drops)IBA
08/2022 - 09/2009
9Retinaldehyde (Retinal)IBA
01/2021 - 11/2010
9auraptenIBA
07/2012 - 05/2002
7TeaIBA
09/2014 - 09/2005
7LigandsIBA
01/2013 - 10/2003
7nobiletinIBA
01/2010 - 10/2002
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2022 - 10/2003
6Biological ProductsIBA
05/2013 - 02/2003
6DNA (Deoxyribonucleic Acid)IBA
03/2011 - 10/2002
6AzoxymethaneIBA
01/2010 - 01/2004
6NF-kappa B (NF-kB)IBA
02/2009 - 05/2005
61'-acetoxychavicol acetateIBA
01/2009 - 02/2002
6Transforming Growth Factor beta (TGF-beta)IBA
05/2008 - 05/2003
5Drinking WaterIBA
07/2021 - 10/2003
5Fluorescein (Funduscein)FDA LinkGeneric
11/2019 - 05/2009
5InterleukinsIBA
08/2015 - 02/2004
5PolyphenolsIBA
09/2014 - 09/2005
5Phorbol EstersIBA
01/2011 - 06/2002
5CarcinogensIBA
01/2010 - 09/2002
5Matrix Metalloproteinases (MMPs)IBA
10/2007 - 02/2005
4Dextrans (Dextran)FDA Link
07/2021 - 10/2003
4sodium sulfate (sodium bisulfate)FDA LinkGeneric
07/2021 - 10/2003
4Heat-Shock Proteins (Heat-Shock Protein)IBA
09/2014 - 11/2011
4FlavonoidsIBA
01/2011 - 01/2002
3AllergensIBA
10/2021 - 02/2009
3Biomarkers (Surrogate Marker)IBA
10/2020 - 10/2003
3MicroRNAs (MicroRNA)IBA
06/2020 - 12/2015
3Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2017 - 04/2006
3retinol palmitate (retinyl palmitate)FDA Link
01/2017 - 01/2012
3Interleukin-33IBA
08/2015 - 10/2009
3Thymic Stromal LymphopoietinIBA
08/2015 - 01/2010
3Therapeutic UsesIBA
11/2013 - 06/2009
3cardamoninIBA
01/2013 - 08/2011
3Interleukin-6 (Interleukin 6)IBA
11/2011 - 11/2005
3Pharmaceutical PreparationsIBA
03/2011 - 07/2004
3Protein Kinases (Protein Kinase)IBA
01/2011 - 05/2008
3aplysiatoxinIBA
01/2011 - 06/2009
3QuercetinIBA
01/2010 - 02/2005
3Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA
02/2009 - 04/2006
3Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2009 - 10/2005
3Superoxides (Superoxide)IBA
10/2007 - 05/2002
3Matrix Metalloproteinase 7 (Matrilysin)IBA
10/2007 - 02/2005
3Scavenger Receptors (Scavenger Receptor)IBA
04/2007 - 05/2006
3oxidized low density lipoproteinIBA
04/2007 - 05/2006
3LDL Lipoproteins (beta Lipoproteins)IBA
04/2007 - 05/2006
3LipopolysaccharidesIBA
04/2006 - 02/2003
3Free RadicalsIBA
04/2006 - 05/2002
3Chymases (Chymase)IBA
12/2005 - 06/2004
2SolutionsIBA
08/2022 - 11/2020
2diquafosolIBA
08/2022 - 01/2022

Therapy/Procedure

9Therapeutics
06/2020 - 01/2003
7Contact Lenses
07/2022 - 03/2007
6Lasers (Laser)
03/2021 - 09/2007
4Light Coagulation
01/2018 - 01/2014
3Topical Administration
08/2022 - 01/2021
3Oral Administration
07/2021 - 01/2009
3Corneal Transplantation (Keratoplasty)
11/2020 - 04/2006
3Chemoprevention
02/2008 - 01/2000